Efeitos da combinação comercial do adoçante dietético líquido composto por sucralose e acessulfame de potássio no bioensaio Allium cepa

Abstract

Sweeteners, also known as dietary sweeteners, are substances capable of providing the sweet taste of sucrose, without presenting a caloric value significant for the organism. Among the various sweeteners available on the market are sucralose and acesulfame potassium, which raise doubts about their possible harmful effects on the body. This study aimed to evaluate the potential cytotoxic and genotoxic compounds of different concentrations of the commercial combination of liquid dietary sweetener composed of sucralose and acesulfame potassium, both artificial. For this, meristematic cells from the Allium cepa bioassay were used. subjected to three different concentrations of sweetener, for 24 and 48 hours, after initial root growth in tap water, which was also used as a control test negative. For statistical analysis, the Graphpad program was used Prism 9.0 with analysis of variance (ANOVA) and application of the Tukey Test. The results obtained in the present experiment demonstrated the absence of cytotoxicity and genotoxicity of the combination of sweeteners analyzed, composed of sucralose and acesulfame potassium.