A EFICIÊNCIA DO USO DE ANTIMICROBIANOS SISTÊMICOS COMO TERAPIA AUXILIAR NO TRATAMENTO DA PERIODONTITE CRÔNICA: UMA REVISÃO INTEGRATIVA DE LITERATURA

Abstract

Chronic periodontitis is characterized as a multifactorial inflammatory disease that affects the supporting tissues of the teeth and is frequently associated with bacterial infections requiring specific therapeutic interventions. Thus, this study aimed to analyze, through a literature review, the effectiveness of systemic antimicrobials as adjunctive therapy in the treatment of chronic periodontitis, as well as the clinical, microbiological, and inflammatory outcomes reported in recent scientific literature. An integrative literature review was conducted using the BVS, LILACS, PubMed, and SciELO databases, selecting articles published within the last five years. The reviewed studies indicated significant improvements in probing depth reduction, decreased gingival bleeding, and increased clinical attachment when antimicrobials were used as adjuncts. The most effective combinations involved amoxicillin associated with metronidazole, particularly in patients with aggressive or refractory periodontitis. However, there was consensus regarding the cautious use of antibiotics to prevent bacterial resistance. Therefore, it is concluded that the judicious use of systemic antimicrobials is beneficial when combined with conventional mechanical treatment and should be guided by clinical and microbiological evidence.