INFLUÊNCIA DA SUPLEMENTAÇÃO DE PROBIÓTICOS EM ÍNDICES METABÓLICOS E NA PRESSÃO ARTERIAL DE MULHERES ADULTAS: UMA REVISÃO DE ESCOPO

Abstract

Arterial Hypertension (AH) is a multifactorial clinical condition characterized by sustained elevation in blood pressure. In women, the prevalence of AH begins to become more evident from the end of the fourth and beginning of the fifth decade of life. With its high prevalence, AH is easy to diagnose and has effective treatment, which can be medicated or non-medicated. The use of foods supplemented with probiotics in the form of dairy products, capsules, fermented foods, among other forms of consumption, are being investigated as treatment strategies for hypertension and other risk factors for cardiovascular diseases. Evidence shows that the intestinal microbiota is associated with the regulation of several systems, including the regulation of BP. Therefore, the objective of the study was to carry out a brief scoping review to map and analyze the effects of the use of probiotics on blood pressure in adult women. The review was conducted in accordance with JBI guidelines; the research question and study eligibility followed the PICO strategy. Furthermore, the PRISMA-ScR extension was used for scoping review. The searches were carried out on the platforms PubMed, SciELO, Lilacs, Virtual Health Library (BVS) and Google Scholar, in duplicate by two independent researchers, using the following keywords: Probiotic, combined with women, and hypertension. 68 articles related to the subject were found on search platforms. After reading the title and abstract, 21 studies were obtained, 10 of which were duplicates in the databases. Therefore, after applying the eligibility criteria, 11 studies were selected for the review. Most studies chose to administer the probiotic through sachets (36.36% - 4 studies), capsules (18.18% - 2 studies) and the remainder of the studies, distributed in powdered milk (9.09% - 1 study), fermented milk (9.09% - 1 study), enriched red clover extract (9.09% - 1 study) and Minas frescal cheese (9.09% - 1 study). 63.63% of the studies (7) did not observe a variation in the value of Diastolic Blood Pressure; 27.27% (3) did not observe significant changes in Systolic Blood Pressure; 45.45% of studies (5) observed a decrease in SBP; 3 of the articles that make up the review (27.27%) did not present data on blood pressure. The use of probiotics as a nutritional strategy for controlling blood pressure in women can be considered promising given the results presented by the studies analyzed, being able to act on metabolic pathways, and risk factors associated with the development of arterial hypertension.