INFLUÊNCIA DO TREINAMENTO DE SPRINTS CURTOS NAS RESPOSTAS INFLAMATÓRIAS DE PESSOAS COM DEPRESSÃO

Abstract

Depression is a psychiatric illness that affects individuals worldwide and causes considerable inconvenience and disability to the patients. Over the years, research around depression shows a direct relationship between depression and inflammation. Therefore, new nonpharmacological strategies are needed for these patients to improve their quality of life. For this reason, short sprint interval training (sSIT) is a potential non pharmacological treatment that could help reduce depressive symptoms. Objective: To verify the serum levels of IL-1β of women with major depressive disorder before and after sSIT. Materials and Methods: This is a randomized controlled study that evaluated 17 sedentary women with a diagnosis of depression, aged 18 to 60 years. Participants were recruited by the psychiatry outpatient clinic of the University Hospital of Campo Grande/MS and randomized into two groups: experimental and control. Assessments were performed using questionnaires, anthropometry, cardiorespiratory testing and blood samples. After the evaluations, the experimental group completed 6 sessions over two weeks, of 4-12 sprints of 5 seconds, with an active rest interval of ≥ 30 seconds at 50W, with a rest of 48 hours between sessions. The control group performed their normal daily activities without exercising. After the training period, all participants performed the same assessments and blood collections again. Finally, analyzes of IL-1β were conducted using the commercial Elisa Assay kit. Results: sSIT showed promising results as a non-pharmacological treatment for depressive symptoms, but there were no significant changes in IL-1β levels after treatment. Conclusion: To obtain greater responses from this type of training in depressive individuals, a greater number of participants is needed to analyze depressive symptoms and inflammatory markers before and after sSIT.