Use este identificador para citar ou linkar para este item: https://repositorio.ufms.br/handle/123456789/631
Tipo: Artigo de Periódico
Título: Development and validation of UV spectrophotometric method for determination of levofloxacin in pharmaceutical dosage forms
Autor(es): Kassab, Nájla Mohamad
Amaral, Marcos Serrou do
Singh, Anil Kumar
Santoro, Maria Inês Rocha Miritello
Abstract: The objective of this research was to develop and validate an alternative analytical method for quantitative determination of levofloxacin in tablets and injection preparations. The calibration curves were linear over a concentration range from 3.0 to 8.0 μg mL-1. The relative standard deviation was below 1.0% for both formulations and average recovery was 101.42 ± 0.45% and 100.34 ± 0.85% for tablets and injection formulations, respectively. The limit of detection and limit of quantitation were 0.08 and 0.25 μg mL-1, respectively. It was concluded that the developed method is suitable for the quality control of levofloxacin in pharmaceuticals formulations.
Palavras-chave: Fluoroquinolonas
Espectrofotometria
Controle de Qualidade
Fluoroquinolones
Spectrophotometry
Quality Control
Editor: Química Nova
Citação: KASSAB, Nájla Mohamad et al . Development and validation of UV spectrophotometric method for determination of levofloxacin in pharmaceutical dosage forms. Quím. Nova, São Paulo, v. 33, n. 4, 2010 . Disponível em <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000400037&lng=pt&nrm=iso>. acessos em 24 out. 2011. http://dx.doi.org/10.1590/S0100-40422010000400037.
Tipo de Acesso: Acesso Aberto
Identificador DOI: http://dx.doi.org/10.1590/S0100-40422010000400037
URI: https://repositorio.ufms.br/handle/123456789/631
Data do documento: 2010
Aparece nas coleções:CCBS - Artigos publicados em periódicos

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