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Tipo: Artigo de Periódico
Título: Presence of anti-toxocara antibodies in children selected at hospital unversitário, Campo Grande, MS, Brazil
Autor(es): Matos, Maria de Fatima Cepa
Militão, Dina Namico Arashiro
Brum, Maria Aparecida R.
Omais, Maruãn
Quilião, Maria Eulina
Dorval, Maria Elizabeth Moraes Cavalheiros
Pereira, Ângela da Costa
Possi, Luís Augusto
Sauer, Leandro
Camargo, Eide Dias
Tundisi, Regina Nardini
Abstract: Visceral Larva Migrans syndrome (VLM) results from the presence or migration of helminth larvae in humans, who nonetheless only play the role of paratenic hosts in the helminths life cycle. In humans, VLM can be caused by larvae of various nematode species, chiefly those of the ascarid Toxocara canis, which can then be found at a variety of body sites, such as the liver, lungs, heart, and brain. Clinical and pathological manifestations depend primarily on larvae number and location, infection duration, reinfection occurrence, and host s immunological condition. Signs and symptoms may range from asymptomatic infection to severe disease. In humans, infection is acquired through ingestion of T. canis eggs present in soil, containing larvae in the infective stage7, 8, 9. Indeed, eggs of Toxocara sp. have been found in sandboxes in several public places in the city of Campo Grande, Mato Grosso do Sul state2. This study was carried out to detect the presence of anti-Toxocara antibodies in children attending the Pediatrics division of Hospital Universitário of Universidade Federal de Mato Grosso do Sul at Campo Grande, Brazil. Over the years 1992-94, 454 serum samples, obtained from children of 5.25 ± 3.28 years of mean age and selected at that hospital on the basis of eosinophil count greater than or equal to 1000/mm3 of blood, were tested for the presence of antibodies by means of the ELISA technique employing Toxocara canis larvae excretory-secretory antigens5. A high prevalence rate for toxocariasis (35.55%) was found, which was observed to be associated with eosinophil levels lower than those usually reported in literature. Furthermore, a higher frequency of positive serology among boys was also observed (13 cases in contrast to only 3 among girls), a result also reported by other authors.
Palavras-chave: Toxocara canis
Eosinofilia - imunologia
Toxocaríase - epidemiologia
ELISA - métodos
Testes Sorológicos
Eosinophilia - immunology
Toxocariasis - epidemiology
Enzyme-Linked Immunosorbent Assay - methods
Serologic Tests
Editor: Revista do Instituto de Medicina Tropical de São Paulo
Citação: MATOS, M. F. C. et al. Presence of anti-toxocara antibodies in children selected at hospital unversitário, Campo Grande, MS, Brazil. Rev. Inst. Med. trop. S. Paulo, São Paulo, v. 39, n. 1, jan. 1997 . Disponível em <>. acessos em 22 ago. 2011.
Tipo de Acesso: Acesso Aberto
Identificador DOI:
Data do documento: 1997
Aparece nas coleções:CCBS - Artigos publicados em periódicos

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