Aspectos diagnósticos, terapêuticos e complicações perinatais em gestantes de alto risco com infecção do trato urinário

Abstract

The symptomatic urinary tract infection (UTI) is common during pregnancy due to the potential anatomical and functional changes. Acquires importance in this period due to maternal or fetal complications, such as anemia, premature rupture of membranes chorioamniotic, preterm delivery, leukomalacia and perinatal death. This study examined the frequency of urinary tract infection, the bacteriological profile, the antimicrobial susceptibility and the association of a history of obstetric and perinatal complications. For this, the data collection was performed using medical records of pregnant women in the study group with urinary tract infection and a comparison group without urinary tract infection, from the Department of High Risk Pregnancy, University Hospital, Federal University of Mato Grosso do Sul during the period April 2005 to April 2010. We analyzed medical records of 864 pregnant women seen at the clinic, 15,6% (135/864) had urinary tract infection. The average age of women with infection was 26,9 6,5 years. Escherichia coli was the most frequent 34,8% (47/135). The E. coli strains were more sensitive to norfloxacin (91,4%), nitrofurantoin (80,8%) and ceftriaxone (74,4%). There was little effect on growth inhibition in vitro to ampicillin (42,5%), trimethoprim-sulfamethoxazole (31,1%) and 1st generation cephalosporins (14,8%). There was a significant association between nephrolithiasis, preterm delivery, low birthweight and urinary tract infection in pregnant women. The use of urine tests from the routine prenatal detection allows early dealings and urinary infection in pregnant women, allowing better perinatal newborn.