Novel santalane sesquiterpenoids from the stem bark of Duguetia glabriuscula - Annonaceae

Abstract

Five novel santalane-type sesquiterpenes were isolated from the stem bark of Duguetia glabriuscula – Annonaceae. Their structures have been established on the basis of spectral data and chemical evidences (1H and 13C NMR, HMQC, HMBC) as (+)-a-santal-10-en-9-ol (1), (+)-a-santalan-10,11-epoxy-9-ol (2), a-santal-11-en-9,10-diol (3), (+)-a-santalan-9,10,11-triol (4), and (+)-a-santalan-9,11-epoxy-10-ol (5). Polycarpol, a triterpenoid, was also obtained.