Use este identificador para citar ou linkar para este item: https://repositorio.ufms.br/handle/123456789/135
Tipo: Artigo de Periódico
Título: End-to-side nerve repair using fibrin glue in rats
Título(s) alternativo(s): Anastomose nervosa término-lateral usando cola de fibrina em ratos
Autor(es): Silva, Daniel Nunes e
Coelho, Julice Medeiros
Frazílio, Fabrício de Oliveira
Odashiro, Alexandre Nakao
Carvalho, Paulo de Tarso Camillo de
Pontes, Elenir Rose Jardim Cury
Vargas, André Ferrão
Rosseto, Marcelo
Silva, Andréia Brochado Antoniolli da
Abstract: PURPOSE: To evaluate axonal regeneration after end-to-side nerve repair with fibrin glue in rats. METHODS: Forty-five Wistar rats were divided into three groups: group A (n=15), were not submitted to surgery (control group); group B (n=15) were submitted to fibular transection without repair; and group C (n=15), were submitted to fibular transection with end-to-side nerve anastomosis using fibrin glue, in the lateral surface of an intact tibial nerve. The three groups were submitted to walking track (30 and 90 days) and posterior morphometrical analysis (90 days).RESULTS: The functional tests demonstrated that there was no difference in the walking track during the study in group A (p>0.05). The group B had walking pattern impairment in the two tests (p>0.05). The group C had walking pattern impairment in the first test, with important recovery in the second test (p<0.05). The morphometrical assessment revealed significantly higher number of regenerated mielinates axons in group C, compared to group B (p<0.05). CONCLUSION: The end-to-side nerve repair with fibrin glue shows axonal recovery, demonstrated through functional and morphometrical ways in rats.
Palavras-chave: Técnicas de Sutura
Adesivo Tecidual de Fibrina
Microcirurgia
Ratos
Suture Techniques
Fibrin Tissue Adhesive
Microsurgery
Rats
Editor: Acta Cirurgica Brasileira
Citação: SILVA, Daniel Nunes e et al . End-to-side nerve repair using fibrin glue in rats. Acta Cir. Bras., São Paulo, v. 25, n. 2, Apr. 2010 . Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502010000200007&lng=en&nrm=iso>. access on 14 July 2011. doi: 10.1590/S0102-86502010000200007.
Tipo de Acesso: Acesso Aberto
Identificador DOI: 10.1590/S0102-86502010000200007
URI: https://repositorio.ufms.br/handle/123456789/135
Data do documento: 2010
Aparece nas coleções:FAMED - Artigos publicados em periódicos

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