Use este identificador para citar ou linkar para este item: https://repositorio.ufms.br/handle/123456789/1194
Tipo: Artigo de Periódico
Título: HIV/AIDS-associated visceral leishmaniasis in patients from an endemic area in Central-west Brazil
Autor(es): Oliveira, Priscilla Alexandrino de
Oliveira, Joanna Reis Santos
Dorval, Maria Elizabeth Cavalheiros
Costa, Francisco das Chagas Brandão da
Pereira, Gracy Regina Oliveira Leite
Cunha, Rivaldo Venâncio da
Paniago, Anamaria Mello Miranda
Cruz, Alda Maria da
Abstract: An increase in morbidity associated with visceral leishmaniasis (VL) in human immunodeficiency virus (HIV)/AIDS patients has been described in Africa and the Mediterranean. Despite the high endemicity of VL and HIV-1/AIDS in Brazil, this association has not been thoroughly investigated. Our aim was to evaluate the epidemiologic and clinical characteristics of VL-HIV-1/AIDS cases from Central-west [Mato Grosso do Sul (MS)] Brazil. Medical records of 23 VL-HIV-1/AIDS patients were reviewed. Patients were predominantly adult males (87%) and 34.8% of the patients were intravenous drug users (IVDU). Leishmaniasis was the first opportunistic infection in 60% of the HIV-1 patients. Fever occurred in all patients, although splenomegaly and hepatomegaly were absent in 21.7% of the cases. CD4+ T-cell counts were below 200 cells/mm3 in 80% of the cases and the counts did not increase after clinical remission despite antiretroviral therapy. The first drug chosen to treat the cases was antimonial, but the therapeutic regimen was altered to amphotericin B in 12 of 17 cases due to side effects. Relapses were reported in 56.5% of the patients. IVDU may constitute an important risk factor for the transmission of both diseases in MS. VL-HIV-1/AIDS patients in MS share similar clinical characteristics as those from other endemic regions worldwide. Thus, these findings are critical for improving the surveillance of VL-HIV/AIDS patients.
Palavras-chave: HIV
Leishmaniose Visceral
Usuários de Drogas
Leishmaniasis, Visceral
Drug Users
Editor: Memórias do Instituto Oswaldo Cruz
Citação: ALEXANDRINO-DE-OLIVEIRA, Priscilla et al . HIV/AIDS-associated visceral leishmaniasis in patients from an endemic area in Central-west Brazil. Mem. Inst. Oswaldo Cruz, Rio de Janeiro, v. 105, n. 5, Aug. 2010 . Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000500016&lng=en&nrm=iso>. access on 10 Apr. 2012.
Tipo de Acesso: Acesso Aberto
Identificador DOI: http://dx.doi.org/10.1590/S0074-02762010000500016.
URI: https://repositorio.ufms.br/handle/123456789/1194
Data do documento: Jan-2010
Aparece nas coleções:CCBS - Artigos publicados em periódicos

Arquivos associados a este item:
Arquivo Descrição TamanhoFormato 
hiv aids associated visceral leishmaniasis.pdf526 kBAdobe PDFThumbnail
Visualizar/Abrir


Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.