É VIÁVEL A REABILITAÇÃO COM IMPLANTES DENTÁRIOS EM PACIENTES COM SÍNDROME DE PAPILLON-LEFÈVRE? UMA REVISÃO DE LITERATURA

Abstract

Papillon-Lefèvre Syndrome (LPS) is a rare, autosomal recessive genetic condition that is characterized by hyperkeratosis on the palms and soles of the feet and by severe periodontitis, leading to the early loss of deciduous and permanent teeth. Caused by mutations in the cathepsin C gene (CTSC), SPL increases susceptibility to infections and impacts patients' quality of life. Rehabilitation with dental implants (IDs) is a viable therapeutic option to regain masticatory and aesthetic function, but it requires close follow-up to prevent complications such as mucositis and peri-implantitis. This study aims to evaluate the success of IDs in patients with LPS by analyzing limitations and challenges and highlighting the importance of an individualized approach. The keywords "Papillon-Lefèvre Disease", "Dental Implants", " Mouth Rehabilitation" and "Peri- implantitis" were used to search for articles in the PubMed and SciELO databases. After analysis, 14 articles were selected, including 16 patients with SPL (138 IDs) and an implant loss rate of 15.2%, resulting in a survival rate of 84.8%. Early failures occurred in two patients due to lack of osseointegration, while late failures, associated with bone loss due to peri-implantitis, were reported in six patients. It is concluded that IDs are a viable alternative, with encouraging results, but it is necessary to carry out more long- term studies with effective control of peri-implant biofilm to obtain more definitive conclusions about the safety and efficacy of this treatment in patients with SPL.