Relatório de Estágio Obrigatório e Trabalho de Conclusão de Curso: Púrpura Hemorrágica Equina/Vasculite Imunomediada em Equino - Relato de caso

Abstract

This report presents the technical documentation of the mandatory curricular internships completed at FMVZ/UNESP – Botucatu, in the Large Animal Surgery Clinic, and at HOVET/FZEA/USP – Pirassununga, in the Equine Medical and Surgical Clinic. The document systematically details the structural organization of the hospital units, operational workflows, clinical and surgical routines, and the diversity of conditions managed, contextualizing the practical experience acquired at both reference institutions. The undergraduate thesis includes an in-depth case report of equine purpura hemorrhagica, emphasizing the initial clinical characterization, progression of systemic lesions, and physical findings consistent with severe vasculitis. Sequential analyses of hematologic and biochemical parameters are presented, highlighting anemia, thrombocytopenia, inflammatory markers, and hypoproteinemia, along with ultrasonographic assessment that identified pleuropneumonia as a secondary complication. Histopathological evaluation revealed leukocytoclastic vasculitis, fibrinoid necrosis, and fibrin thrombi. The study discusses the therapeutic approaches employed such as immunosuppression, clinical support, management of complications, and monitoring of disease progression correlating the patient’s response to treatment with the underlying pathophysiology. The final discussion underscores the severity and clinical challenges associated with immune-mediated vasculitis in horses.