Comparação da atividade antimicrobiana do timol e carvacrol à clorexidina em cirurgias

Abstract

Introduction: There is an ongoing search for new chemical compounds through plant extracts and phytochemical compounds that do not generate as many side effects in the oral cavity and which have good antimicrobial properties. Objective: to evaluate the synergistic antimicrobial efficacy of chelating solutions containing thymol and carvacrol and to compare them with chlorhexidine mouthwash 0.12% after the extraction of symmetrical lower third molars. Methods: Nineteen (n=19) healthy individuals aged 18 to 30 years old, of both sexes, attending the Faculdade de Odontologia do Mato Grosso do Sul (UFMS) participated in this study. All patients were submitted to two different therapeutic treatments, divided into two groups: group 1 (control) - the participant had a chlorhexidine mouthwash 0.12%; group 2 (experimental) - the participant made a mouthwash with 0.05% thymol solution and 0.025% carvacrol solution. The suture was removed postoperatively for 7 days and transferred aseptically to a tube containing sterile saline of potassium buffer. The samples were sent to the Laboratory of Microbiology of the UFMS, for microbiological analysis. Results: Mean and standard deviation of Colony Forming Units / ml of microorganisms isolated from suture yarns grown in BHI Agar obtained from the control group was 4,766 x 106 ± 4,069 while the experimental group was 4.847 x 106 ± 3.971. Conclusion: The thymol-based and carvacrol-based mouthwash is effective in the antimicrobial activity in the adherence of the biofilm in silkwires after the extraction of third molar teeth.