Caracterização das hospitalizações por anemia falciforme no Estado do Mato Grosso do Sul

Abstract

Sickle cell disease is a common hereditary hematological disease in Brazil. It encompasses a group of hemolytic anemias, which are characterized by structural changes in the beta-globin chain that lead to the production of an abnormal hemoglobin called HbS. Sickle cell anemia (SCA) stands out among these hemoglobinopathies. In Brazil, due to the historical context of African migration, of a slave nature, SCA expanded throughout almost the entire national territory and today is part of a group of relevant diseases and conditions that affect several individuals. It is estimated that around 3,500 newborns with SCA and 200,000 with sickle cell trait are diagnosed each year by the Brazilian National Neonatal Screening Program.