EFEITOS DO LASER DE BAIXA INTENSIDADE ASSOCIADO AO GEL DE SILICONE E TRATAMENTO CONVENCIONAL EM MODELO ANIMAL PARA LESÕES POR QUEIMADURA

Abstract

Burn injuries are considered severe forms of tissue damage due to their ability to destroy deeper tissues and lead to pathological changes in the dermis and subcutaneous tissue. Advances have been observed in the treatment of burns, but they are still considered a complex area due to the high risk of infection and susceptibility to chronicity of these wounds. Therefore, complementary therapies are important to accelerate the process of tissue repair. The objective of the study was to analyze the effects of low-intensity laser associated with silicone gel and 1% silver sulfadiazine in an animal model of burn injuries. This is an experimental study, with 21 days of follow-up, which was carried out with 72 Wistar rats. To perform the experiment, the animals were allocated into 6 groups, which received different treatments regarding the use of the topical product and wavelength of laser therapy. The laser was applied every 48 hours, punctually, at a single point in the center of the lesion, with a wavelength of red (660 nm) and infrared (808 nm), with a dose of 1 J. Macroscopic, morphometric and microscopic aspects were evaluated. It was observed that the application of the laser at a wavelength of 808 nm, with a dose of 1 J, associated with silicone gel, presented satisfactory effects for healing, mainly on the 11th and 21st days, with better results in the rate of contraction of the lesion.