https://repositorio.ufms.br/handle/123456789/9939 2026-07-26T13:50:27Z https://repositorio.ufms.br/handle/123456789/14535 Título: Estado da arte das raias na bacia do alto rio Paraná (Chondrichthyes, Potamotrygonidae) Abstract: The occurrence of the freshwater stingrays, Potamotrygon amandae and Potamotrygon falkneri, in the upper Paraná River basin represents one of the most significant recent changes in the distribution of neotropical ichthyofauna, resulting from the elimination of the biogeographic barrier of Sete Quedas Falls after the making of the Itaipu Reservoir. This study aimed to provide a state of the art review of these species in the upper Paraná river basin, addressing aspects related to their natural history, distribution, morphology, physiology, reproduction, conservation status, accidents involving humans, and ecological impacts associated with their expansion. Therefore, a literature review was conducted based on scientific articles, books, theses, dissertations, and technical documents. The analyzed studies indicate that these species show high ecological plasticity, broad adaptability to different habitats, and specialized reproductive strategies, characteristics that have favored their establishment and dispersal throughout the upper portion of the Paraná River. Furthermore, their presence has been associated with ecological changes and an increase in accidents involving fishermen and swimmers, representing an important challenge for environmental management and public health. Thus, the synthesis of available information contributes to expanding knowledge about these species and provides support for future monitoring, conservation, and environmental education initiatives. Tipo: Trabalho de Conclusão de Curso 2026-01-01T00:00:00Z https://repositorio.ufms.br/handle/123456789/14452 Título: Nova espécie de Astyanax Baird & Girard (Characiformes: Acerthorhamphidae) das drenagens dos rios Madeira e Tapajós, Mato Grosso, Brasil Abstract: Uma nova espécie de Astyanax é proposta para as bacias dos rios Juruena e Aripuanã, Mato Grosso, Brasil. A nova espécie difere de seus congêneres por apresentar duas máculas umerais, a primeira verticalmente alongada e a segunda aproximadamente arredondada com início na faixa longitudinal negra; presença de um dente no osso maxilar (ou dente ausente); duas séries de dentes no pré-maxilar: a externa com 4-5 dentes (moda 4), pentacuspidados; série interna com 4-5 (moda 5), heptacuspidados base da nadadeira anal recoberta por duas séries de escamas cobrindo até dois terços de sua extensão; nadadeira anal com v,22-27 raios; linha lateral com 34-37 escamas perfuradas. A espécie é relativamente comum nas drenagens das ecorregiões do Madeira (rio Aripuanã) e Tapajós-Juruena. Tipo: Trabalho de Conclusão de Curso 2026-01-01T00:00:00Z https://repositorio.ufms.br/handle/123456789/14122 Título: Impactos farmacogenéticos de polimorfismos do sistema endocanabinoide em pacientes com esquizofrenia Abstract: Schizophrenia (SCZ) is a chronic and highly debilitating psychiatric disorder affecting approximately 24 million people worldwide, including 1.6 million in Brazil. Therefore, it has a significant economic impact. Among patients, 34% constitute a group that does not respond well to conventional antipsychotics, individuals with treatment-resistant schizophrenia (TRS). In these cases, the gold-standard treatment is clozapine (CLZ), even though it is often underutilized. The pathophysiology of SCZ, as well as its causes, is not fully elucidated and remains under study. The endocannabinoid system (ECS) has been identified as a mediator of the stress and inflammation that occur in SCZ, as well as in other psychiatric disorders. This study aimed to investigate the association between polymorphisms in ECS genes and the use of CLZ in patients with SCZ, as an indicator of TRS. We evaluated Ninety-five patients followed up in a specialized outpatient clinic, diagnosed with SCZ and using antipsychotics. Clinical and sociodemographic data were obtained, and symptomatic severity was assessed using the Positive and Negative Syndrome Scale (PANSS). Peripheral blood samples were used for genotyping of the rs7766029 (CNR1), rs35761398 (CNR2), and rs324420 (FAAH) polymorphisms by real-time PCR with TaqMan™ probes. Genotypes were compared between users (n=12) and non-users of CLZ (n=83) using association and logistic regression tests. There was an association between the CNR1 or CNR2 polymorphisms and CLZ use in a recessive inheritance pattern (p < 0.05). In an adjusted logistic regression model, the homozygous mutant genotype of CNR1 (CC) was associated with an increased chance of using CLZ (OR = 11.5; p = 0.001; 95% CI: 2.81 - 47.39), as well as a trend towards increased use in the homozygous mutant genotype of CNR2 (OR = 3.55; p = 0.08; 95% CI: 0.85 - 14.77). The FAAH polymorphism did not show a significant association. Despite sample limitations and the absence of functional analyses, the findings suggest that variants in SEC genes may be related to treatment refractoriness in SCZ, reinforcing the potential of this system as a target for personalized therapeutic approaches. Tipo: Trabalho de Conclusão de Curso 2025-01-01T00:00:00Z https://repositorio.ufms.br/handle/123456789/14092 Título: COMPOSIÇÃO TAXONÔMICA DA AVIFAUNA COMO INDICADORA DE REGENERAÇÃO EM UMA ÁREA DE CERRADO DEGRADADO EM TRÊS LAGOAS, MS Abstract: Birds are bioindicators of degraded areas due to their easy access; however, few studies evaluate this parameter in Cerrado areas. Therefore, we analyzed the role of avifauna in indicating ecological restoration by associating its taxonomic composition with a regenerating Cerrado area and comparing it with preserved local Cerrado phytophysiognomies (cerradão, cerrado stricto sensu, várzea, and riparian forest) during dry and rainy seasons. The avifauna composition in the recovering Cerrado at the beginning of the regeneration process showed high similarity to the várzea, due to structural similarities, while the other phytophysiognomies remained dissimilar to these two environments. After 12 years, the previously degraded Cerrado shows signs of regeneration, evidenced by the divergence in the taxonomic composition of the avifauna in the recovering Cerrado compared to open areas and greater similarity to more forested environments, although it has not yet reached its climax. Tipo: Trabalho de Conclusão de Curso 2025-01-01T00:00:00Z